Infectious diseases like Vibriosis, Red Disease and White Spot Syndrome would causes to a major production and economic losses. Hence, an adequate treatment of water before stocking as well as while running culture would be regularly maintained in order to reduce multiplication and spread of pathogens in the culture ponds. Triple Star has the potential to destroy wide range of pathogens of economic importance in aquaculture farming therefore it can reduce the incidence of disease outbreak and to enhance survivability.